Object : To analysis the effect of negative or positive behavior symptoms in stroke patients on cognitive function, activity of daily living (ADL) and improvement of quality of life (QOL).
Methods : Sixty-seven patients for first-ever stroke hospitalized at Wonkwang University hospital were enrolled. Positive and negative syndrome scale (PANSS) was used for measure the behavior symptoms and we investigate the general characteristic of patients. We apply K-MMSE, CDR, KDSQ for cognitive assessment, K-MBI, FAC for evaluation of ADL, BDI for depression assessment, EQ-5D for QOL, and K-NIHSS, MRS for neurological assessment. Each scale was re-evaluated at 1 month and 3 month.
Result : The overall average age was 63.8 years and mean duration of stroke participated in the study time was 1.1 ± 0.4 months. (Table 1) There were showed significant improvement in K-MMSE, CDR, KDSQ, K-MBI, FAC BDI, EQ-5D, K-NIHSS and mRS after 1month and 3month. (p<0.05, table 2) There were showed significant difference in all PANSS after 1month and 3month except for a positive scale after 1month. (p<0.05, table 2) When compared the prevalence of each item of PANSS according to time, all measures were shown to be reduced after the rehabilitation. Delusions, excitement and represents the highest prevalence in positive scale, emotional withdrawal, passive/apathetic social withdrawal, and blunted affect shows higher prevalence in negative scale, and in order of depression, somatic concern and disorientation showed a high prevalence in general psychopathology scale. There was a positive correlation between the BDI and composite score after 1month and 3month, but there was a negative correlation between the mRS and composite score after 3months and the remaining scales did not show statistical significance (Table 3) .
Conclusion : There were significant difference in all positive and negative symptoms after 1month and 3month. There were showed that general symptoms is the highest incidence and that was followed by negative symptoms and positive symptoms. Effects of behavioral symptoms on cognitive function, ADL and QOL were did not showed a statistically significant difference
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