제목 | The Effect of Different Viscosities on Pharyngeal Pressure during Swallowing |
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소속 | Daegu Fatima Hospital, Department of Rehabilitation Medicine1, Seoul National University Bundang Hospital, Department of Internal Medicine-G-I/Hepatology2, Seoul National University Bundang Hospital, Department of Rehabilitation Medicine3 |
저자 | Donghwi Park1*, Cheol Min Shin2, Ju Seok Ryu3† |
Objectives: To investigate and compare the mechanism of swallowing with respect to the viscosity of ingested material between healthy subjects and patients with dysphagia.
Design: Prospectively collected and retrospectively analyzed clinical study. Setting: General teaching hospital, rehabilitation unit Participants: We retrospectively reviewed the high resolution manometry (HRM) results of 35 patients with dysphagia symptoms. Additionally, we included 18 healthy individuals as controls. Based on VFSS results, we classified patients into two groups, one with aspiration and the other without aspiration. Intervention: Swallowing of a 5mL thin liquid and 5mL honey-like liquid (Yoplait) in all patients. Main Outcome Measures: HRM of various variables during the swallowing process. Results: There was no significant difference between thin liquid and honey-like liquid (Yoplait) with respect to parameters for high-resolution manometer in the healthy control, as well as in the non-aspiration and aspiration groups. However, in a comparison between thin liquid and honey-like liquid with respect to visuospatial and timing variables, the degree of differences in the maximal pressure of velopharynx (VP) in the aspiration group was significantly larger than the healthy control and non-aspiration group (p<0.05). Conclusion: Our results indicate that there is a clear difference in the degree of adaptation to viscosity between the three groups—healthy subjects, patients with aspiration, and patients without aspiration. These differences may provide an explanation for the mechanism of swallowing, which may be useful for the treatment of dysphagia. |
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File.1:
Figure 2_300dpi.GIF
The diagram of HRM parameters of thin liquid and honey-like liquid (Yoplait) swallowing in the heathy control, non-aspiration group, and aspiration group. (A)(B) In the aspiration group, maximal pressure of VP, maximal pressure of low pharynx, pre-UES max
File.2:
Figure 3_300dpi.GIF
The diagram of HRM parameters according to viscosity changes in the heathy control, non-aspiration group, and aspiration group. (A-F) There was no significant difference of HRM parameters between 5mL of thin liquid and 5mL of thick liquid (Yoplait) in the
File.3:
Figure 4_300dpi.GIF
The differences of maximal pressure of VP was significantly larger in the aspiration group compared with the healthy control and non-aspiration group (p<0.05) The differences of low pharynx maximal pressure was significantly larger in the aspiration group
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