| 제목 |
Low skeletal muscle mass and spasticity in male patients with spinal cord injury |
| 소속 |
Seoul National University Hospital, Department of Rehabilitation Medicine1 |
| 저자 |
Hyung-Ik Shin 1†, Seungwoo Cha 1, Jae-Hyun Yun 1* |
Introduction: It is well-known that spasticity and loss of skeletal muscle mass occur after spinal cord injury. Both spasticity and muscle atrophy restrict activities of daily living and impairs quality of life, but there are few studies about their relationship. Therefore, the objective of this study is to investigate the association between skeletal muscle mass and spasticity in Korean patients with spinal cord injury.
Methods: Fifty six male patients with spinal cord injury were included. Spasticity was assessed using spasticity sum score and Penn spasm frequency test. Low skeletal muscle mass was defined by appendicular skeletal muscle mass divided by height squares. Laboratory tests including hemoglobin, albumin, creatinine, fasting glucose, and cholesterol were performed.
Results: Mean age was 42.3 years and 37 patients (66.1%) were complete injury (ASIA A). Forty seven patients (83.9%) showed low skeletal muscle mass. They showed significantly lower body mass index (BMI), waist circumference, serum creatinine level, and spasticity than patients with normal skeletal muscle mass. Low skeletal muscle mass was significantly correlated with decreased spasticity score. BMI was the only significant variable in logistic regression analysis for low skeletal muscle mass.
Conclusions: Low skeletal muscle mass is prevalent in patients with spinal cord injury. Low skeletal muscle mass was significantly correlated with decreased spasticity.
Key words: spinal cord injury; sarcopenia; spasticity; muscle atrophy
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Table 1. Demographics
Table 2. Characteristics of spinal cord injury patients with low skeletal muscle mass
Table 3. Spearman’s correlation between skeletal muscle mass and spasticity
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