| 제목 |
Correlation between Diffusion Tensor Fractional Anisotropy and Functional Outcomes in stroke |
| 소속 |
Chungnam National University, School of Medicine, Department of Rehabilitation Medicine1 |
| 저자 |
Dongmin Hwang1*, Youngwook Kim1, Min Kyun Sohn1† |
1. Objective
Fractional anisotropy (FA) measured by diffusion tensor imaging (DTI) represents neural fiber integrity and directionality of white matter tract. This study aimed to determine whether fractional anisotropy of the corticospinal tract is useful to predict functional outcome at a month after stroke onset.
2. Subject & Method
Medical records of 75 subacute stroke patients who admitted to rehabilitation center from August 2017 to February 2018 were reviewed retrospectively. Patients were classified into 2 groups by whether the FA value of affected side is measured or not : incompletely disrupted group and completely disrupted group. The FA ratio (the FA of affected side divided by that of unaffected side) and fiber number (FN) ratio of corticospinal tract were calculated to determine the correlation with functional outcome in incompletely disrupted group. Functional outcomes from a month after stroke onset were measured by functional independence measure (FIM), Fugl Meyer assessment (FMA) of upper extremity and lower extremity, trunk impairment scale (TIS), berg balance scale (BBS), and length of stay (LOS). In addition, incompletely disrupted group was compared with the group with completely disrupted group for functional outcome differences.
3. Result
The motor component of FIM, FMA of upper extremity, and BBS were positively correlated and LOS was negatively correlated with FA ratio (Table 2). Table 3 showed that incompletely disrupted group was significantly higher in FMA of upper extremity, TIS and BBS at one month after stroke onset and lower in LOS than in completely disrupted group.
4. Conclusion
This study found that the FA value of corticospinal tract can be a good predictor of functional outcomes and LOS for subacute stroke patients. Further prospective study should be needed for determining the predictability of diffusion tensor imaging for functional recovery in stroke patients. |
|
table1
table2
table3
|
