| 제목 |
Contributing factors to exercise induced desaturation in pulmonary arterial hypertension |
| 소속 |
Pusan National University Hospital, Department of Rehabilitation Medicine1, Pusan National University Hospital, Department of Internal Medicine-Cardiology2 |
| 저자 |
Ji Won Hong1, Jung Hyun Choi2, Ji Yeon Shin2, Yong Beom Shin1, Jae Hyeok Chang1, Myung Jun Shin1, Mi Kyung Cho1, Byeong Ju Lee1*† |
Objective
To evaluate the prevalence of exercise induced desaturation (EID) and elucidating the contributing factors in pulmonary arterial hypertension (PAH) patients.
Methods
Analyze 20 pulmonary arterial hypertension patients’ data (EID group = 10) from April 2016 to May 2018.
Comparisons of background characteristics, comorbidity, trans-thoracic echocardiography (TTE), cardiac catheterization, pulmonary function test (PFT), 6MWT with gas analysis, body composition test and muscle power test between EID and non-EID patients were conducted.
Results
Epidemiological characteristics, TTE data and cardiac catheterization data did not differ between 2 groups.
Forced expiratory volume in the first second (FEV1), 6MWD and peak oxygen consumption (VO2peak) were significantly low in EID group(Table 1).
We suggest a “predictive scale for exercise induced desaturation in pulmonary arterial hypertension (PSEID)” (table 2). As PSEID is 4 or more, it showed 80% of sensitivity and 90% of specificity.
Conclusion
The EID was found in the half of PAH patients and FEV1, 6MWD and VO2peak were most relevant factors. Result of TTE and cardiac catheterization was not correlated with EID. |
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Pulmonary function and 2-minute walk test data
Predictive scale for exercise induced desaturation in pulmonary arterial hypertension (PSEID)
Sensitivity and specificity of PSEID
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