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연제번호 : OP-Scientific 2-2 북마크
제목 The Effect of Early Outpatient Rehabilitation Program Among Heart and Lung Transplant Recipients
소속 Daegu Catholic University Medical Center, Department of Rehabilitation Medicine1, National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Physical Medicine and Rehabilitation2, Fu Jen Catholic University Hospital and Fu Jen Catholic University School of Medicine, Department of Physical Medicine and Rehabilitation3, National Taiwan University Hospital and National Taiwan University College of Medicine, Department of Surgery4, Fu Jen Catholic University Hospital and Fu Jen Catholic University School of Medicine, Department of Surgery5
저자 Dae Gil Kwon1*, Hung-Jui Chuang2, Ssu-Yuan Chen2,3†, Hsao-Hsun Hsu4, Shoei-Shen Wang4,5, Ching Lan2, Nai-Kuan Chou4, Jang-Ming Lee4, Yih-Sharng Chen4, Ron-Bin Hsu4, Jin-Shin Lai2
Objective –The purpose of this study is to investigate the effect of an early postoperative outpatient rehabilitation program to physical capacity and health-related quality of life among patients with bilateral sequential lung transplantation (BLTx) or orthotopic heart transplantation (OHT).

Method –The study included 19 clinically stable BLTx patients (age: 41.5 ± 13.3 years; 8 men, 11 women) and 29 OHT patients (age: 42.4 ± 12.1 years; 19 men, 10 women). The patients started outpatient rehabilitation at 78 ±47 days after transplantation and participated in a 3-6 months supervised exercise training program. The physical capacity of study subjects was evaluated by the cardiopulmonary exercise testing (CPET) and health-related quality of life by the Medical Outcomes Trust 36-item health survey (SF-36) at baseline and upon the completion of rehabilitation.

Results – After outpatient rehabilitation, the BLTx patients exhibited a significant increase of peak oxygen uptake (16.9 ± 3.4 to 19.6 ± 4.9 mL/kg/min, p=.002) as well as OHT patients (15.4 ± 3.4 to 20.4 ± 3.7 mL/kg/min, p< .001). Both groups showed improvement of physical component in health-related quality of life. The OHT group showed a significant improvement of SF-36 scores in physical functioning (64.7 ± 22.4 to 80.2 ± 13.8), bodily pain (62.2 ± 24.3 to 76.1 ± 23.0), vitality (56.2 ± 22.6 to 67.2 ± 17.7), social functioning (65.1 ± 25.1 to 76.7 ± 16.9), mental health (66.5 ± 17.6 to 72.6 ± 16.1), and PCS (38.8 ± 10.8 to 44.3 ± 10.5). The BLTx group showed a significant improvement of SF-36 scores in physical functioning (72.6 ± 16.4 to 85.8 ± 17.9), physical role (42.1 ± 44.1 to 86.8 ± 32.7), general health (62.5 ± 18.1 to 69.9 ± 17.1), vitality (63.9 ± 21.4 to 74.7 ± 15.1), social functioning (69.1 ± 27.4 to 86.8 ± 15.9), emotional role (66.7 ± 44.4 to 91.2 ± 24.4), mental health (69.3 ± 20.8 to 77.7 ± 12.4), and PCS (42.5 ± 10.1 to 51.7 ± 8.1).

Conclusions – Early postoperative exercise training significantly improved physical capacity and health-related quality of life among BLTx and OHT patients. Early postoperative outpatient rehabilitation program should be recommended to heart and lung transplantation recipients.
File.1: Table 1.jpg
Table 1. Baseline Demographic and Clinical Characteristics
File.2: Table 2.jpg
Table 2. Functional Capacity and Quality of Life Before and After Training